Find hotels in Santo Spirito, Florence from $76

While Santo Spirito is unique in its combination of local life and artistic heritage, other neighborhoods that offer a comparable experience in Florence include Oltrarno and San Niccolò.

Oltrarno, meaning "across the Arno," encompasses Santo Spirito itself but also extends further west and south. It's known for its artisan workshops, particularly leather goods and jewelry, and its narrow, winding streets. This area is ideal for travelers who appreciate authentic Florentine craftsmanship and a more local feel away from the main tourist crowds. You'll find many small trattorias and independent shops here.

San Niccolò, located just east of Santo Spirito along the Arno River, offers a similar blend of residential charm and proximity to attractions. It sits at the foot of Piazzale Michelangelo, providing easy access to panoramic city views.

Two highly recommended hotels in Santo Spirito are the Bernini Palace and the Helvetia & Bristol Firenze – Starhotels Collezione.

The 5-star Bernini Palace, with an outstanding 9.6 rating, is celebrated for its superb location, beautiful and clean rooms, and exceptional service. Guests particularly appreciate the friendly and amazing staff, and the excellent breakfast. It is conveniently located near Piazza Santo Spirito, Via de' Tornabuoni, and the Santo Spirito Basilica, all within half a mile.

Another excellent choice is the 5-star Helvetia & Bristol Firenze – Starhotels Collezione, rated 9.2. This hotel is praised for its excellent location and helpful staff. It features rainfall showerheads and premium bedding, ensuring a comfortable stay. Key attractions like Piazza Santo Spirito, Via de' Tornabuoni, and the Santo Spirito Basilica are all within 0.4 miles.

For family-friendly hotels in Santo Spirito, consider the Four Seasons Hotel Firenze, Hotel De La Ville, Bernini Palace, FH55 Grand Hotel Mediterraneo, and Rivoli Boutique Hotel.

The 5-star Four Seasons Hotel Firenze, with an exceptional 9.8 rating, offers a variety of family amenities including free rollaway extra beds and cribs, supervised childcare, and babysitting services. Kids' meals are available, and the hotel provides a playground for children. It is conveniently located near Piazza Santo Spirito and the Tower of San Niccolo. Guests consistently praise its great location and excellent service.

Another excellent choice is the 4-star Hotel De La Ville, rated 9.2. This hotel provides sofa beds, free cribs, and onsite babysitting services. It is very close to Piazza Santo Spirito and Via de' Calzaiuoli. Travelers frequently highlight the friendly and great staff, spacious and clean rooms, and great breakfast.

The 5-star Bernini Palace, boasting a 9.6 rating, offers free cribs and onsite babysitting. It is perfectly situated within easy reach of Piazza Santo Spirito and Via de' Calzaiuoli. Guests praise the friendly and amazing staff, beautiful and clean rooms, and excellent breakfast.

The 4-star FH55 Grand Hotel Mediterraneo, rated 8.0, provides onsite babysitting, rollaway extra beds, highchairs, and free cribs, suiting families. It is located close to the Tower of San Niccolo and Piazzale Michelangelo. Reviewers appreciate the friendly and helpful staff, as well as the good food and great breakfast.

Finally, the 4-star Rivoli Boutique Hotel, with a 9.0 rating, features sofa beds and free cribs, along with connecting rooms for larger families. It is situated near Piazza Santo Spirito and Via de' Calzaiuoli. Guests frequently mention the beautiful and great location, extremely helpful staff, and delicious breakfast.

For 5-star hotels in Santo Spirito, consider the Bernini Palace, Helvetia & Bristol Firenze – Starhotels Collezione, Four Seasons Hotel Firenze, Hotel Lungarno - Lungarno Collection, and Floren Hotel.

The 5-star Bernini Palace, with an impressive 9.6 rating, offers premium bedding, designer toiletries, and 24-hour room service. Guests frequently praise the friendly and amazing staff, the beautiful and clean rooms, and the excellent breakfast. It is conveniently located just 0.3 miles from Via de' Tornabuoni and 0.5 miles from Piazza Santo Spirito.

Another excellent option is the 5-star Helvetia & Bristol Firenze – Starhotels Collezione, rated 9.2. This hotel provides a luxurious experience with a rainfall showerhead, premium bedding, bathrobes, and a Turkish bath or hammam. Reviewers consistently highlight the excellent and helpful staff and the top rooms. It's situated 0.2 miles from Via de' Tornabuoni and 0.4 miles from Piazza Santo Spirito.

The 5-star Four Seasons Hotel Firenze boasts an outstanding 9.8 rating. This hotel features air conditioning, suites, bathrobes, and designer toiletries. Guests appreciate the great location and excellent service. It is located 0.9 miles from Via de' Tornabuoni.

The 5-star Hotel Lungarno - Lungarno Collection, with a 9.6 rating, offers river views, designer toiletries, and air conditioning. Guests consistently praise the friendly and absolutely wonderful staff, the cozy and clean rooms, and the great breakfast. Its location is highly regarded, being just 0.1 miles from Via de' Tornabuoni and 0.2 miles from Piazza Santo Spirito.

Finally, the 5-star Floren Hotel, rated 9.4, provides premium bedding, air conditioning, and 24-hour room service. Travelers often praise the excellent and friendly staff, the nice and clean rooms, and the delicious breakfast. It is well-located, just 0.3 miles from Via de' Tornabuoni and 0.2 miles from the Salvatore Ferragamo Museum.

For the best spa hotels in Santo Spirito, you have several excellent choices including Palazzo Castri 1874 Spa & Garden, Hotel Spadai, Hotel La Gemma, Four Seasons Hotel Firenze, and Helvetia & Bristol Firenze – Starhotels Collezione.

The 4-star Palazzo Castri 1874 Spa & Garden, boasting an impressive 9.8 rating, offers an extensive spa experience with hot stone massages, deep tissue massages, body wraps, and facials. Guests particularly appreciate the beautiful garden and the wonderful spa facilities. It is conveniently located less than a mile from Piazza Santo Spirito and Santo Spirito Basilica.

Another superb option is the 4-star Hotel Spadai, also with a 9.8 rating. Its full-service spa provides a range of treatments including Ayurvedic therapies, deep tissue massages, and aromatherapy. The hotel is praised for its spacious rooms and its superb location, a short walk from Piazza Santo Spirito and the Salvatore Ferragamo Museum.

The 5-star Hotel La Gemma, rated 9.6, features an onsite spa offering Swedish massages, hot stone massages, and manicures and pedicures. Travelers frequently highlight the friendly staff, amazing location, and gorgeous rooms. It is very close to Piazza Santo Spirito and the Salvatore Ferragamo Museum, both within 0.4 miles.

The 5-star Four Seasons Hotel Firenze, with a 9.8 rating, provides a full-service spa with hot stone massages, hydrotherapy, and body scrubs. Guests consistently praise the excellent service. This hotel is located about a mile from Piazza Santo Spirito.

Finally, the 5-star Helvetia & Bristol Firenze – Starhotels Collezione, rated 9.2, offers a full-service spa with hot stone massages, deep tissue massages, and a Turkish bath. The staff are described as excellent and helpful, and the location is considered beautiful, very close to Piazza Santo Spirito and the Salvatore Ferragamo Museum.

For hotels in Santo Spirito that offer free breakfast, consider the Hotel David, Stella d'Italia, Hotel Horto Convento, Flom Boutique Hotel, and Bernini Palace.

The 3-star Hotel David, rated 10.0, provides a wonderful complimentary breakfast buffet, along with free self-parking and free WiFi. Guests consistently praise the excellent and friendly staff, and the comfortable, clean rooms. It is conveniently located near the Tower of San Niccolo, just 0.4 miles away.

Another excellent choice is the 4-star Stella d'Italia, also rated 10.0. This hotel offers a free buffet breakfast and free WiFi. It is situated in a shopping district and is very close to the Santo Spirito Basilica, only 0.3 miles away. Guests frequently mention the superb location and excellent breakfast.

The 4-star Hotel Horto Convento, with a 9.8 rating, features a complimentary buffet breakfast and an airport shuttle available 24 hours a day. Guests appreciate the comfortable and clean rooms, and the excellent, quiet location. It is 0.4 miles from Santo Spirito Basilica.

The 4-star Flom Boutique Hotel, rated 9.8, also provides a free breakfast buffet and a 24-hour airport shuttle. Travelers often highlight the helpful and amazing staff, along with the modern, clean rooms and comfortable beds. It is within walking distance of the Fountain of Neptune, just 0.6 miles away.

For a luxurious option, the 5-star Bernini Palace, rated 9.6, offers a free breakfast buffet and is part of Historic Hotels of the World. This hotel is in a historical district and also provides a 24-hour airport shuttle. It is very close to the Fountain of Neptune, only 0.1 miles away, and guests frequently praise the friendly staff and beautiful, clean rooms.

For top pet-friendly hotels in Santo Spirito, consider Hotel Lungarno - Lungarno Collection, 25hours Hotel Florence Piazza San Paolino, Gallery Hotel Art - Lungarno Collection, Bernini Palace, and Starhotels Michelangelo.

The 5-star Hotel Lungarno - Lungarno Collection, with an excellent 9.6 rating, is a pet-friendly option that welcomes dogs and provides amenities such as litter boxes and food and water bowls. Guests consistently praise the friendly staff, cozy and clean rooms, and the great breakfast and restaurant. It is conveniently located just 0.2 miles from Piazza Santo Spirito.

Another great choice is the 4-star 25hours Hotel Florence Piazza San Paolino, rated 9.4. This hotel is pet-friendly for both dogs and cats, offering food and water bowls, and features a terrace and furnished patio. Guests frequently mention the spacious and amazing rooms, excellent staff, and brilliant breakfast. It is situated 0.4 miles from Piazza Santo Spirito.

The 4-star Gallery Hotel Art - Lungarno Collection, also with a 9.4 rating, is another highly-rated pet-friendly hotel that welcomes dogs and provides litter boxes and food and water bowls. Visitors often praise the excellent staff, great location, and spacious rooms with super comfortable beds. It's only 0.3 miles from Piazza Santo Spirito.

The 5-star Bernini Palace, with a superb 9.6 rating, is a pet-friendly hotel where pets stay free, welcoming both dogs and cats. It provides food and water bowls and is located in a historical district. Guests frequently highlight the friendly staff, great location, beautiful and clean rooms, and exceptional breakfast. It is 0.5 miles from Piazza Santo Spirito.

Finally, the 4-star Starhotels Michelangelo, rated 8.6, is a pet-friendly option where pets stay free, accommodating both dogs and cats. It offers food and water bowls and is known for its exceptional and helpful staff and great location. It is 0.8 miles from Piazza Santo Spirito.

For top boutique hotels in Santo Spirito, you have excellent options such as Hotel Horto Convento and Hotel Kraft.

The 4-star Hotel Horto Convento, with an outstanding 9.8 rating, is highly praised for its friendly and helpful staff, comfortable and clean rooms, and excellent, quiet location. Guests particularly enjoy the beautiful and delicious breakfast and the exceptional service. It's conveniently located just 0.4 miles from Piazza Santo Spirito and Santo Spirito Basilica.

Another excellent choice is the 4-star Hotel Kraft, rated 9.4. Guests frequently mention the spacious and clean rooms, amazing and friendly staff, and convenient location. The hotel also offers covered self-parking and valet parking options, and its breakfast and food receive excellent reviews. It's located just 0.6 miles from Piazza Santo Spirito and Santo Spirito Basilica.

Also consider the 4-star Grand Hotel Baglioni, which has a 9.0 rating. This hotel is celebrated for its superb location, excellent and friendly staff, and a great bar. It also provides a 24-hour airport shuttle and free WiFi. It is conveniently situated 0.6 miles from Piazza Santo Spirito.

The 3-star Hotel Caravaggio, with a 9.0 rating, is another great boutique option. Guests consistently praise the friendly and helpful staff, the beautiful and clean rooms, and the fantastic breakfast. It offers free WiFi and is located 0.9 miles from Piazza Santo Spirito.

Finally, the 3-star Hotel Machiavelli Palace, rated 8.4, is top for its convenient location and friendly, absolutely wonderful staff. Guests appreciate the beautiful and always clean rooms, and the great food. Some rooms also feature a private rooftop hot tub or a balcony. It is located 0.7 miles from Piazza Santo Spirito.

For budget-friendly hotels in Santo Spirito that offer excellent value, consider the Hotel David, Hotel Pendini, Hotel Accademia, Hotel Delle Nazioni, and Corona D'italia.

The 3-star Hotel David, with a superb 10.0 rating, stands out for its exceptional service and amenities. Guests appreciate the complimentary buffet breakfast and free self-parking, as well as the free minibar items. It is conveniently located just 0.4 miles from the Tower of San Niccolo.

Another highly-rated option is the 3-star Hotel Pendini, with a 9.6 rating. This hotel is praised for its great location, being only 0.2 miles from the Fountain of Neptune and 0.4 miles from Santo Spirito Basilica. It offers a full breakfast at no additional cost and free WiFi.

The 3-star Hotel Accademia, rated 9.2, is also an excellent choice, offering free continental breakfast and free WiFi. Its location is frequently highlighted by guests, being only 0.6 miles from Santo Spirito Basilica and 0.4 miles from the Fountain of Neptune.

The 3-star Hotel Delle Nazioni, with an 8.4 rating, provides a 24-hour airport shuttle service, making it very convenient for travelers. Guests enjoy the complimentary breakfast and free WiFi. It is located 0.4 miles from Medici Chapels.

Lastly, the 3-star Corona D'italia, also rated 8.4, offers free WiFi and a complimentary buffet breakfast. Its location is often noted as excellent, with the Fountain of Neptune just 0.6 miles away.

For a romantic getaway in Santo Spirito, couples should consider the Hotel Spadai, Palazzo Castri 1874 Spa & Garden, Art Hotel Villa Agape, or the luxurious Four Seasons Hotel Firenze.

The 4-star Hotel Spadai, with an outstanding 9.8 rating, offers a full-service spa with couples' treatment rooms, Ayurvedic treatments, and a Turkish bath, providing a truly relaxing experience. Guests appreciate its spacious and beautiful rooms, and it is conveniently located near Piazza Santo Spirito and Via de' Tornabuoni.

Another excellent choice for couples is the 4-star Palazzo Castri 1874 Spa & Garden, also rated 9.8. This hotel features a full-service spa with a hot tub, sauna, and couples' treatment rooms, superb for unwinding together. The beautiful garden is often praised by guests, and the hotel is close to the Santo Spirito Basilica.

The 4-star Art Hotel Villa Agape, with a 9.8 rating, provides a romantic setting with its beautiful rooms and a hot tub for guests to enjoy. It also offers a free area shuttle and an airport shuttle, making transportation easy. The hotel is situated near Piazza Santo Spirito.

For a truly luxurious romantic experience, the 5-star Four Seasons Hotel Firenze, rated 9.8, is an exceptional option. It boasts a full-service spa with hot stone massages, body wraps, and a steam room, ensuring a pampering stay. Some rooms even feature balconies, adding to the romantic ambiance. The hotel is located near Via de' Tornabuoni and the Palatine Gallery.

For hotels in Santo Spirito near Via de' Calzaiuoli, consider the Hotel Calimala Florence and Hotel La Gemma.

The 4-star Hotel Calimala Florence, with a 9.6 rating, is just 0.1 miles from Via de' Calzaiuoli. Guests appreciate its terrace and options for balconies, including a rooftop terrace. Reviews frequently mention the friendly and helpful staff, as well as the great location and clean rooms.

Another excellent option is the 5-star Hotel La Gemma, also rated 9.6, and also located just 0.1 miles from Via de' Calzaiuoli. This hotel offers valet parking, air conditioning, and premium bedding. Guests consistently praise the friendly staff, great location, and gorgeous rooms.

The best time to visit Santo Spirito, Tuscany, is during the spring (April to June) and fall (September to October) when the weather is pleasant and the region is less crowded.

For couples seeking a romantic getaway, spring offers mild temperatures and the Tuscan countryside in full bloom. You can enjoy leisurely strolls through vineyards and olive groves, savor al fresco dining, and explore charming towns without the intense summer heat. The spring months also offer various local festivals, providing an authentic cultural experience.

Travelers looking for a culinary experience will find fall to be an ideal time. The autumn harvest brings truffle festivals, grape harvests, and olive oil pressing events. The weather remains comfortable for exploring, and you can indulge in seasonal Tuscan dishes and wine tastings.

You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santo Spirito.

Prices for hotels in Santo Spirito often vary, but you can find a great deal from $76 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.